Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal ... understanding of how these cells contribute to the tumor response to hypoxia in non-small-cell lung cancer.

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, accounting for 80 to 85% of all cases of lung cancer. There are different stages of NSCLC, ranging from 0 to 4; ...

The epithelial–mesenchymal transition is the process by which polarised epithelial cells that are connected via adhesion lose their characteristics and acquire migratory and invasive properties ...

2016); however, their ability to recapitulate the characteristics of the adult tissue remains to be fully defined. Airway epithelial cells serve as a first line of defense against pathogen attack or ...

Study uncovers a pathogenic subset of memory T-cells that promote tissue inflammation and highlights a potential target for treating nasal polyps and other inflammatory airway diseases.

Lung cancer remains the leading cause of cancer-related deaths globally, with cigarette smoking as its primary driver.

The data generally provide solid evidence that transformed epithelial cells exhibit higher compressibility than wild-type cells, a property linked to their compaction during mechanical cell ...

60-year-old founders are approximately three times more likely to build a successful venture than 30-year-old entrepreneurs. One of the major reasons is their access to a powerful professional ...

Organoids are small, lab-grown structures that resemble ... standardized and animal-free alternative. Human airway cells grown on an Invasin coating as 2D organoid sheets produce high numbers ...

A research team has successfully utilized human respiratory organoids (mini-organs) to propagate human rhinovirus C (HRV-C), ...