On day 1, GLP-1 was infused to stimulate endogenous insulin release and suppress endogenous glucagon. On days 2–5, pancreatic endocrine clamps were performed using somatostatin infusions of ...

alpha cells that release glucagon, beta cells that release insulin and delta cells that release somatostatin. The results provide an underlying explanation for how the reduced proportion of ...

Diameters of islets and area of insulin- and glucagon-labeled cells within islets on each section were measured with the aid of image analysis software (ImageJ). Numbers of islets, defined as ...

A new study has uncovered a critical role for the enzyme Glucose-6-phosphatase 2 (G6PC2) in regulating blood sugar levels.

beta cells secrete insulin, and alpha cells secrete glucagon. Scientists have identified three additional cell types in islets, including cells that secrete the hormones somatostatin, ghrelin ...

New findings raise the possibility of promising therapeutic strategies for the management of hypoglycemia in type 1 diabetes ...

Acromegaly is due to hypersecretion of growth hormone and insulin-like growth factor I ... Medical treatment of the disease is usually with somatostatin analogs. An open, prospective, single ...

Insulin isophane suspension (NPH) (human, rDNA origin) 100 Units/mL; susp for SC inj. Instruct patients on proper administration of insulin, check insulin label before each injection, and ...

May need to adjust antidiabetic agents. Octreotide acetate is a potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Like somatostatin, it also suppresses LH response to ...