In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs ...

More information: Hideki Kobayashi et al, Regeneration of Nonhuman Primate Hearts With Human Induced Pluripotent Stem Cell–Derived Cardiac Spheroids, Circulation (2024). DOI: 10.1161 ...

PSCs pack themselves into clusters called spheroids, where they encounter microenvironments like those they experience in the body. "Pluripotent stem cells like to be in contact with each other ...

In a large-animal model study, researchers have found that heart attack recovery is aided by the injection of heart muscle cell spheroids derived from human-induced pluripotent stem cells (hiPSCs ...

Organoids are self-organizing, three-dimensional structures derived from adult or induced pluripotent stem cells. They provide a unique physiologically ... organoids and other 3D culture systems such ...

Spheroids remain viable and pluripotent when grown 4 ... scalable expansion of neural stem cells (NSCs) and neural progenitor cells, and earlier onset of neuronal maturation and functional activity.