Traditionally, therapies combining DNA-damaging agents and STING agonists have shown potential in treating cancer by enhancing immune response and reshaping the tumor microenvironment. However ...

The activation of the intracellular transmembrane receptor stimulator of interferon genes (STING) has shown antitumoral effects in murine cancer models.

The fatality is considered to be related to the drug treatment, according to the biotech, which is developing the STING agonist in collaboration with GSK under the terms of a $1.3 billion option ...

In 2013, a synthetic STING agonist, 5,6-dimethylxanthenone-4-acetic acid (DMXAA), showed tremendous anticancer efficacy in mice but failed in human clinical trials because the murine and human ...

The dosing of patients with advanced sarcoma and Merkel cell carcinoma by intravenous infusion of Curadev's systemic allosteric STING agonist, CRD3874-SI, has been initiated in a Phase 1a/b dose ...

Mukesh Ambani lauds PM Modi's vision for self-reliance in energy sector, says no power can stop India's growth trajectory ...