The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

The order of Cdk-substrate dephosphorylation depends in part on the timing of Cdk inactivation ... The same is true for cell division: chromosome duplication comes first, after which the ...

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some ...

Females carry two X chromosomes, after inheriting one from each parent. In order to stop serious problems from arising, cells of the body silence one... | Genetics And Genomics ...

Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication 1. These findings ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

Several mathematical models for cell inactivation and its dependency on the dose-rate are included. Central themes are also the variation in radiosensitivity with the cell-cycle stage, radiomodifying ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Patient was not fit for Docetaxel therapy and he was put on monthly Denosumab injection 120 mg/1 syringe, and Abiraterone ...

Our editors also may be in touch with follow-up questions. T-Mobile has been in the telecommunications business since 1994 when it was known as VoiceStream Wireless. Today, it’s one of the ...