Mutations acquired after conception in single HSCs and haematopoietic progenitor cells were used as lineage markers (Fig. 1a). Given that such mutations occur about once every three weeks 2 ...

The results suggest that the human stomach has a unique geographical distribution of lineages with acid secreting cells throughout the antrum. These findings suggest that lineage derivation in the ...

Broadwood Partners, L.P., a significant stakeholder in Lineage Cell Therapeutics, Inc. (NYSE:LCTX), has acquired a substantial amount of the company's common shares. The acquisition, valued at $6 ...

CARLSBAD, Calif.--(BUSINESS WIRE)--$LCTX #LineageCellTherapeutics--Lineage Cell Therapeutics, Inc. (NYSE American and TASE: LCTX), a clinical-stage biotechnology ...

This is especially problematic in cases of blocked blood vessels, which can repeatedly starve large areas of the heart of ...

While NOTCH guides thymus progenitors toward T cell fate, the absence or disruption of NOTCH signaling renders the thymus microenvironment permissive to other cell fates. Following T cell commitment, ...

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The activation and polarization of T cells play a crucial role in atherosclerosis and dictate athero-inflammation. The epigenetic enzyme EZH2 (enhancer of zeste homolog 2) mediates the H3K27me3 ...

Department of Cardiovascular Medicine, The University of Tokyo, Bunkyo-ku, Japan. (H. Yagi, H.A., Q.L., A.S.-K., M.U., H.K., R.M., A.S., S.O., H.T., Norifumi Takeda ...