The results showed that pA151R reduced the phosphorylation levels of IRF3 and NF-κB induced by cGAS and STING in a dose-dependent manner (Figures 2C, D). These results indicate that pA151R interferers ...

Activated TRAF6 can recruit the kinase RIP1 and activate the TAK1 complex and IKK complex, leading to the activation of NF-κB and MAPKs. TRIF also promotes the TRAF3-dependent activation of the TBK1 ...

Request permissions for this article. Department of Neurology, Sun Yat-Sen Memorial HospitalSun Yat-sen University Guangzhou 510120 China Brain Research Center, Sun Yat-sen Memorial HospitalSun ...