Soluble guanylate cyclase (sGC) is a key signal-transduction enzyme, which converts GTP to the second messenger cGMP in response to signalling from gaseous ligands, particularly nitric oxide (NO).

Overall, the life expectancy of patients with SCD is lower than that of persons without SCD. 1 However, life expectancy varies depending on the type of disease, treatments administered, and ...

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“Like someone is jamming a knife in me,” he said. But for a brief moment on a recent December morning, Wedam, 19, who has sickle cell disease, allowed himself to believe what his doctors had ...