Prolonged rapid eye movement (REM) sleep latency was linked with Alzheimer's disease biomarkers, cross-sectional data showed.

"If you can reduce tau phosphorylation ... slow-wave sleep and elevated levels of tau tangles and amyloid-beta protein. In this latest study, Lucey and colleagues wanted to find out if improving ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

This line of inquiry follows animal model and stem cell studies in which efavirenz reduced the accumulation of both amyloid beta and tau. It’s hypothesized that accumulation of cholesterol in ...

Seventeen clinical scenarios developed for which amyloid or tau PET may be considered. HealthDay News — Appropriate use criteria (AUC) for the use of amyloid and tau positron emission tomography ...

For decades, researchers have produced numerous AD drugs targeting amyloid beta only for them to fail in clinical trials. Scientists have only shifted focus more recently to developing anti-tau ...

“The discovery that tau phosphorylation can act as a protective ... investigate other pathogens that might interact with tau (or [beta-amyloid]) in Alzheimer’s, and test potential therapies ...