Research indicates that the cytokine IL-21 plays a significant role in modulating the balance between Th17 cells, which promote inflammation, and Tregs, which suppress it. An imbalance favoring ...

The therapeutic management of Sjögren syndrome (SjS) has not changed substantially in recent decades: treatment decisions remain challenging in clinical practice, without a specific therapeutic target ...

1 Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan 2 Noster Inc., Kyoto, Japan Objective: We aimed to evaluate microbiome and ...