Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

The "If I Didn't Love You" singer came up with a plan when she was first introduced to the pro athlete Taylor Hill/FilmMagic Carrie Underwood and her husband, Mike Fisher, have experienced ...

Zverev agreed with an adamant Paul that one of the American’s first serves during their first set tie-break had clipped the net, but the chair umpire had not heard the contact. The decision ...

A heart-lung machine is a piece of medical equipment that temporarily takes over the work of the heart and lungs, circulating oxygenated blood throughout the body. Also called a cardiopulmonary bypass ...

Discover a microscopic world with one of the best microscopes for students and young scientists, without emptying your wallet — here are our top picks. The best microscopes for students should ...

The best sewing machine makes your sewing projects easier, whether you're mending clothes or making them from scratch. We've tested sewing machines from popular brands – including Brother, Janome, ...

Image credit: Thermo Fisher Scientific Inc. Thermo Fisher Scientific plans to drive share gain, execute mergers and acquisitions (M&As), and benefit from a gap in the sterile fill-finish market due to ...

In A Complete Unknown, director James Mangold and actor Timothée Chalamet present Dylan as an enigma – a mythology favoured by fans, biopics and the singer himself. By Kate Mossman Rock biopics.