The ability of thiazide-type diuretics to reduce BP seems to be linked to the presence of functioning renal tissue; thus, these drugs will not reduce BP in hemodialysis patients. [6] ...
The manner in which thiazide-type diuretics reduce BP in the long term does not involve a "daily" diuresis. An appreciation of this is important since "diuresis" is an important tool in resistant ...
Hemoconcentration induced by thiazide diuretics could also play a part in producing apparent hyperuricemia in a manner opposite to that suggested to explain the hypouricemia observed after ...
It is thought that thiazide diuretics might prevent osteoporosis by reducing renal calcium secretion. Bolland and colleagues previously conducted a 2-year controlled, blind study in postmenopausal ...
For example, it can interact with anticoagulants and thiazide diuretics. An interaction can occur because one substance causes another substance to have a different effect than expected.
Increases serum lithium levels. May increase toxicity of methotrexate. May decrease effect of furosemide, thiazide diuretics. Increased risk of GI bleed with alcohol. Peptic ulcer or perforation ...