Reproduced with permission from Gultekin et al, Brain 2000; 123: 1481–94 (Oxford University Press). Figure 5 Hypothesis of autoimmune pathogenesis of paraneoplastic syndromes of the CNS. An ...

Paraneoplastic neurologic syndromes (PNSs) are remote effects of cancer with an immune-mediated pathogenesis ... and anti-Tr (associated with Hodgkin lymphoma) and anti-CRMP-5 (associated with ...

Ravulizumab had an early and sustained clinical effect which contributed to the avoidance of intubation. A patient with thymoma-associated myasthenia gravis (MG) was successfully treated with ...

Muhammad Haroon, being a Specialist Registrar, is seeking a dual accreditation in Rheumatology and General Medicine. He is a graduate of King Edward Medical College Lahore, Pakistan and did his ...

Skinmed. 2005;4(2):84-92.

Eculizumab effectively reduced MG-ADL scores and corticosteroid use in thymoma-associated myasthenia gravis patients by week 12. The monoclonal antibody targets complement protein C5, preventing ...

Two-thirds of people with post-COVID-19 syndrome have persistent, objective symptoms—including reduced physical exercise capacity and reduced cognitive test performances—for a year or more ...

What is Cushing's syndrome? Cushing's syndrome is a hormonal disorder. It’s caused when you have high levels of the hormone cortisol over a long time. Cushing's syndrome is fairly rare. It most often ...

Lambert-Eaton myasthenic syndrome (LEMS) is a rare neuromuscular junction disorder. Underlying small cell lung cancer is found in more than half of patients. Proximal muscle weakness, autonomic ...

Personality disorders are deeply ingrained, rigid ways of thinking and behaving that result in impaired relationships with others and often cause distress for the individual who experiences them.