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Nature:线粒体转移,癌细胞免疫逃逸的秘密武器?
该研究首次揭示了一种新型免疫逃逸机制,即癌细胞能够将自身的线粒体转移到T细胞中,从而通过直接干扰T细胞的能量代谢和功能来削弱其免疫活性。这种线粒体转移并非随机事件,而是一个受调控的过程,涉及癌细胞通过细胞间物质传递网络(如纳米管、外泌体等)与T细胞进 ...
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