Recent research has focused on the therapeutic potential of tolerogenic dendritic cells (tolDCs) in both autoimmune conditions and organ transplantation. These specialized cells can induce a state ...

Dendritic cells (DC) offer hope that the treatment of end-stage cancer will become much more successful in the near future. Hundreds of dendritic cell-based therapeutic vaccines have already been ...

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

The interplay among epithelial cells, immune cells (dendritic cells, T cells, B cells, and macrophages), and microbial metabolites in maintaining immune homeostasis is highlighted. 3.1 Receptors for ...

Results: Single-cell analysis revealed distinct immune cell subtypes and indicated an increased presence of myeloid dendritic cells (mDCs) in patients with periodontal disease. MR analysis identified ...

From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...

Epithelial-derived thymic stromal lymphopoietin (TSLP) is an immunoregulatory cytokine playing a crucial role in immune tolerance in the gut via conditioning dendritic cells to expand regulatory T ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some ...

Share on Pinterest Do all our cells have a type of memory, and if so, how might this influence health? We investigate. Design by MNT; Photography by Grant Faint/Getty Images & Ed Reschke/Getty Images.

The presence of two types of hair cells, the inner and outer hair cells, in the organ of Corti was appreciated nearly a 100 years ago but the function of the two has only become clear in the last 20 ...