拷贝数改变在三阴性乳腺癌患者中经常发生。在这里,作者确定了FAD合成酶(FLAD1)在TNBC中作用的拷贝数扩增,并从机制上证明了这种扩增通过FLAD1/LSD1/SREBP1轴增加脂质代谢来驱动肿瘤发生。
【导读】最常见的淋巴瘤类型是 B 细胞淋巴瘤(BCL)。靶向 BCL 的新型疗法改善了许多患者的预后。然而,约 30%患有侵袭性 BCL ...
In her latest Instagram post, Anjali Mukerjee explains the meaning of triglycerides and how the condition affects our body.
Gut microbiota plays a critical role in childhood obesity by influencing energy metabolism, inflammation, and appetite ...
High-carb foods can help regulate your blood sugar and insulin, improve your cholesterol and triglyceride metabolism, and aid in digestive health. General guidelines recommend that 45-65% of your ...
His team identified PanK4 as a key regulator of energy metabolism in skeletal muscle, regulating glucose uptake and fatty acid oxidation and being activated by physical exercise. The study suggests ...
Certain foods like chilli peppers and cacao, boost your metabolism and contribute towards weight loss, supporting optimal ...
A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and ...
The genes included those involved in the function of energy-producing mitochondria, lipid and iron metabolism, and the ...