In the new study, which focused on breast cancer, the authors report that tumor-associated macrophages (TAMs), a type of immune cell found abundantly in the tumor microenvironment, respond to the ...

activating nearby antigen presenting cells (APCs), notably dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 phenotype. In addition to direct phagocytosis of ...

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

Rakesh Jain Ph.D., Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

and tumor-associated macrophages as well as uncovering crucial adaptive T cell regulation pathways in cancer. Using murine genetic cancer models and patient tumor specimens, we were the first to ...

The Arkansas Integrative Metabolic Research Center will host Jeffrey Rathmell, a professor of pathology, microbiology and immunology from Vanderbilt University on Wednesday, Jan. 22.

Therefore, hypoxia is generally associated with more aggressive ... tissue health and fighting infections. In the tumor microenvironment, macrophages are usually reprogrammed to suppress the ...

How would you summarize your study for a lay audience?Ependymoma (EPN) is a common form of brain cancer in children, with few ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...