【导读】肿瘤相关巨噬细胞（TAMs）通常被认为是肿瘤发生和肿瘤发展的帮凶。然而，肿瘤细胞促使 TAMs 协助逃避免疫监视的确切机制仍有待进一步研究。1月24日，浙江大学医学院附属第一医院郑树森院士研究团队在期刊《Advanced ...

activating nearby antigen presenting cells (APCs), notably dendritic cells (DCs), and repolarizing tumor-associated macrophages (TAMs) toward an M1 phenotype. In addition to direct phagocytosis of ...

and tumor-associated macrophages as well as uncovering crucial adaptive T cell regulation pathways in cancer. Using murine genetic cancer models and patient tumor specimens, we were the first to ...

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

In the new study, which focused on breast cancer, the authors report that tumor-associated macrophages (TAMs), a type of immune cell found abundantly in the tumor microenvironment, respond to the ...

Rakesh Jain Ph.D., Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk ...

The study introduces an innovative tracer targeting CD163, a molecular receptor on tumor-associated macrophages—immune cells that support tumor growth and protection. The tracer is based on ...

The European Commission (EC) has approved sugemalimab (brand name: Cejemly®) in combination with platinum-based chemotherapy for the first-line treatment of patients with metastatic NSCLC with no ...

How would you summarize your study for a lay audience?Ependymoma (EPN) is a common form of brain cancer in children, with few ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...