【导读】结直肠癌(CRC)是全球最常见的癌症之一,肝转移是其致死的主要原因。环状 ...
【导读】溶酶体靶向嵌合体(LYTAC)策略,为降解膜蛋白提供了一种非常强大的工具。然而,LYTACs(抗体-小分子共轭物)的合成具有挑战性。基于抗体的LYTACs穿透实体瘤的能力也很有限,尤其是穿越血脑屏障(BBB)的能力。在这项研究中,团队提出了一 ...
Proteomic analysis (proteomics) refers to the systematic identification and quantification of the complete complement of proteins (the proteome) of a biological system (cell, tissue, organ ...
Hartmut received his PhD from the University of Vienna for his work on ubiquitination and the cell cycle carried out in the group of Jan-Michael Peters. In his postdoctoral work in the laboratory of ...
Colorectal cancer, also known as bowel cancer, is a cancer formed by uncontrolled cell growth in the colon or rectum (parts of the large intestine), or in the appendix. Genetic analysis shows that ...
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