In those six patients where long term follow up data were available and in whom no evidence of a “white dot” syndrome was present, two were noted to develop a diffuse outer pigmentary retinopathy.
Electroretinogram of both eyes showed extinguished photopic as well as scoptopic responses. A diagnosis of posterior microphthalmos with pigmentary retinopathy was made. The patient was counselled ...
Late atrophy may represent degeneration of cells that were injured subclinically at the time of initial drug exposure. Although thioridazine toxicity produces an evolving pigmentary disturbance, ...