V-161, a novel compound targeting the Na+ -V-ATPase enzyme in vancomycin-resistant Enterococcus faecium (VRE), significantly reduces bacterial growth and colonization.

A recent study by a team from Chiba University has demonstrated a promising approach for fighting antibiotic resistance by identifying a compound, V-161, that inhibits a sodium-pumping enzyme critical ...

MRSA was once eradicated reliably by vancomycin (Vancocin AE), an antibiotic of the glycopeptide class. With time, the MRSA bacteria became resistant to vancomycin and vancomycin-resistant ...

The major objective of this research collaboration is to develop new therapeutic drug candidates which target antimicrobial resistant pathogens. This work will utilize the Immuron technology platform, ...

There were no drug-related treatment withdrawals or no drug-related serious adverse events, or other safety findings of concern. In the phase 2b vancomycin control arm, 14 out of 14 patients ...

Conjunctival bacteria showed increased resistance to fluoroquinolones, particularly coagulase-negative Staphylococcus species, necessitating cautious antibiotic use. Vancomycin and third-generation ...

Aims: Our aim was to demonstrate that lysozyme-directed generation of gold nanoclusters (Au NCs) are potential antimicrobial agents for antibiotic-resistant bacteria and broad labeling agents for ...

1 Department of Fibre and Polymer Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden 2 Department of Materials, ...