Dysfunctional endothelium displays activation of vascular NADPH oxidase, uncoupling of endothelial nitric oxide synthase, increased expression of endothelin 1, a changed balance between the ...

Long-term stabilizing of retinal exudation and fluid accumulation contributes to brolucizumab’s efficacy in managing wet age-related macular degeneration (AMD). Visual prognosis could be improved when ...

In a groundbreaking study led by Dr. Ying Chen and her team from Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, researchers have uncovered a novel mechanism behind endothelial ...

Atherosclerosis involves multiple processes including endothelial dysfunction, inflammation, vascular proliferation and matrix alteration. Vascular proliferation contributes to the pathobiology of ...

Nitric oxide exerts a fundamental protective role against cardiovascular disease onset by regulating blood pressure and vascular tone, inhibiting leukocyte adhesion and platelet aggregation, and ...