“The whole point of condensates is to separate biological reactions to help them work efficiently, but now when you have ...

This is a useful study that adds new data to how different DAG pools influence cellular signaling, and dissects how the enzyme Dip2 modulates the minor lipid signaling DAG pool, which is distinct from ...

Autophagy, the cell's essential housekeeping process, involves degrading and recycling damaged organelles, proteins, and ...

In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...

Researchers from Weill Cornell Medical School (New York, USA) have found a "mortality timer" in the human body. They claim ...

This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate ...

Smaller nucleoli slow aging, acting as a "mortality timer," while larger nucleoli lead to cell death by destabilizing rDNA. The secret to cellular youth may lie in maintaining a small nucleolus—a ...

School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan 523808, P. R. China Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab of Biomaterials, CAS Key ...

whereas the pericellular generation of adenosine and the intracellular transfer of cyclic AMP through membrane gap junctions expose the target cell to two potently inhibitory molecules.