The paper presents a streamlined new approach for functional validation of genes known to underlie fragile bone disorders in a relatively high throughput, using CRISPR-mediated knockouts and a number ...

Notch1 is expressed uniformly throughout the mouse endocardium during the initial stages of heart valve formation, yet it remains unclear how Notch signaling is activated specifically in the AVC ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AUTS2 syndrome patients often exhibit ...

Professor Sun Yonghua (front) shows zebrafish disease models to members of his research team in the laboratory at the China Zebrafish Resource Center in Wuhan, Hubei province. CHINA DAILY The ...