The figure illustrates the distinct mechanisms of action of dobutamine and levosimendan. Dobutamine mainly activates β1-AR, leading to both beneficial effects (blue lines) through increased cAMP ...

代谢组学和转录组学分析显示，SHTB通过激活G蛋白偶联受体信号和cAMP-PKA通路，增强了WAT的脂解作用及BAT的代谢产热，为了验证SHTB促进脂解以及促进 ...

Secondary endpoints were to evaluate the differences in Opioid Growth Factor Receptor (OGFR), cyclic adenosine monophosphate (cAMP) production and protein kinase A (PKA) in the matched sample and from ...

However, ≈30% of the patients with CPVT required an implantable defibrillator. RyR2 mutations linked to SCD could alter the PKA phosphorylation modulation of the channel by increasing PKA targeting to ...