2021). This capability is essential for understanding the complete structure and function of RNA, including secondary structures and complex genomic regions vital for designing effective vaccines.
The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...
CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.
Cellscript), so other firms could also license the fundamental technology allowing mRNA to function as a therapeutic. In fact, while Moderna, CureVac, BioNTech, and GSK historically dominated mRNA ...
This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...