In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

Amino acids, particularly isoleucine, have also been shown to stimulate milk synthesis through the activation of the mTOR pathway and the expression of sterol regulatory element binding protein 1c ...

uhnresearch.ca Objectives Mammalian target of rapamycin (mTOR) (a serine/threonine protein kinase) is a major repressor of autophagy, a cell survival mechanism. The specific in vivo mechanism of mTOR ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. mTOR plays a pivotal role in cancer growth ...

Research has linked creatine levels with improved protein synthesis (production), highlighting its role in maintaining and growing lean muscle tissue. The body naturally produces creatine in the ...

One of mTOR's roles is to regulate the translation of messenger RNA into protein, so when it's activated, cells produce more protein. This protein synthesis is essential for stem cells to proliferate.

On the other hand, mTOR inhibition would also reduce overall cellular protein translation. This aspect of mTOR inhibition can also potentially contribute to the alleviation of disease phenotype and ...

Faculty of Chemistry, University of Wrocław, Joliot-Curie 14 Street, 50-383 Wrocław, Poland ...

People with diabetes should eat as much protein as people who don't have diabetes. In a healthy diet, roughly 10% to 35% of your daily calories should come from protein. Protein itself does not have ...

The study tested 160 products from 70 top protein powder brands, representing 83% of the market Anna Blazhuk/Getty Protein powders used to build muscle mass can contain harmful heavy metals like ...