See how small bits of non-coding RNA target mRNA for destruction and regulate gene expression. Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species.

RNAi therapeutics are inspired by a mechanism that exists in all cells to regulate gene expression, using specially-designed small interfering RNA (siRNA) that is complementary to specific human ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

More information: Shireesha Manturthi et al, Nanoparticles Codelivering mRNA and SiRNA for Simultaneous Restoration and Silencing of Gene/Protein Expression In Vitro and In Vivo, ACS Nanoscience ...

The oversubscribed Series B will boost the clinical development of two RNAi therapies for epilepsy and Huntington’s disease ...