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A woman was killed after blowing a tire on I-64 and being hit head on by oncoming traffic, resulting in a three-vehicle crash on Wednesday evening.

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ST. LOUIS — Police are investigating a deadly wrong-way crash that happened early Friday morning on Interstate 64 near downtown St. Louis.

A motorist died early Friday after his car was hit by a wrong-way driver on Interstate 64 in St. Louis. "They wouldn't let go ...

Louis. The crash was about 1:45 a.m. on westbound I-64 near South Jefferson Avenue, police said. Three vehicles were involved. A Dodge Ram pickup truck was heading east in the westbound lanes of I-64.

The driver of the Dodge Ram, a 22-year-old man ... It is unclear where the pickup driver entered I-64 the wrong way. “That’ll be part of our investigation to determine if there was impairment.