Tumor-Secreted Protein May Hold the Key to Better Treatments for Deadly Brain Tumor Jan. 8, 2025 — A study has found targeting a protein called endocan and its related signaling pathway could be ...

Additionally, VPA treatment augmented the antitumor activity of NKG2D CAR-T cells in a glioblastoma xenograft model in vivo ... 3.2 μM of VPA or PBS vehicle control was used to pretreat target tumor ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Pictures showing the aftermath of a car fire on the A172 in Middlesbrough have been revealed, as the road reopens. Emergency services were called to Marton Road (A172) in Middlesbrough at around ...

When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...

Effect size analysis indicated that 5FU had the most substantial impact, followed by the combination treatment, while DOX showed a moderate effect in reducing tumor growth (Supplementary Table S1).

We discuss the challenges such as immunosuppressive microenvironment, tumor heterogeneity, and physical barriers that limit CAR-T efficacy. Emerging strategies, such as logic-gated and dual-targeting ...