The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.

Metaphase chromosome preparations made from CUTLL1 cell line were subjected to G banding and karyotype analysis following standard procedures. Two PAC clones RP11-370H5 and CTD-3242B16 ...

Run a brief analysis at the single-cell level, let’s use the common Seurat pipeline. set.seed(12345) sc <- CreateSeuratObject(counts = sc.counts, project = proj.name, meta.data = sc.meta) sc ## An ...

With increasing interest in developing antifibrotic therapies, there is a need for cell lines that preserve the in vivo phenotype of human HSCs to elucidate pathways of human hepatic fibrosis. We ...

Jan. 30, 2025 — A research group has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells. This groundbreaking research opens doors ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

They cross the blood-brain barrier (BBB) under the action of chemokines and enter the brain parenchyma, subsequently migrating to the glioma TME and undergoing phenotypic changes upon contact with ...

Patients who were anti-AQP4 antibody-positive were more commonly treated with monoclonal antibodies, whereas the use of immunosuppressive therapies was often prescribed for patients with anti-AQP4 ...

He was a little coy on pricing, saying that it would be in line with other cell-based therapies that deliver long-term clinical benefits. The company is also developing MSC therapies for other ...

A ransomware group called RansomHouse appears to have been responsible for an attack on Cell C that compromised the data of some of its clients. A ransomware group called RansomHouse appears to have ...