Here, the authors report the acetylation-dependent and acetylation-independent mechanism for the ENL–MOZ complex formation and show the colocalization of ENL and MOZ at active promoters.
This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...
For the multifaceted and complex diseases, multi-omics could define groups of patients with distinct endotypes exhibiting heterogeneous treatment responses due to their particular underlying molecular ...
Activating agents enable the efficient preparation of organozinc complexes from zinc metal and organohalides, but their mechanisms had been obscured by the heterogeneous nature of these systems.
From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...
A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around ...
Lately, Acetyl L-Carnitine, a known supplement, has attracted increasing attention. This supplement is a byproduct of L-Carnitine, an amino acid naturally present in the human body. Acetyl L ...
Scientists investigating Alzheimer’s disease have made a key breakthrough, identifying a vital cellular mechanism driving the most common cause of dementia. The research from the City University ...