Figure 2. Crosstalk between the GPCR and JAK2-STAT5 signaling pathways. AC, adenylyl cyclase; cAMP, cellular adenosine 3’,5’-cyclic monophosphate; GPCR, G protein-coupled receptor; JAK2, Janus kinase ...

Announcing a new article publication for BIO Integration journal. Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

ASC, apoptosis-associated speck-like protein containing a C-terminal caspase recruitment domain; ATP, adenosine triphosphate; BHB ... It blocks the activation of NLRP3 inflammasome independent of ROS, ...

Patients with EGFR-mutated non-small cell lung cancer treated with osimertinib experienced more cancer therapy-related cardiac events than those treated with other EGFR tyrosine kinase inhibitors.

a Academic Ziekenhuis Leiden, Stafcentrum Reumatologie, Leiden, The Netherlands, b Division of Immunology and Allergy, Geneva University Hospital, Geneva, Switzerland Professor F C Breedveld, Academic ...