The activation of adenylate cyclase and production of cyclic adenosine monophosphate (cAMP ... however the phosphoinositide 3-kinase/protein kinase B (PI3K/Akt) and ERK1/2/MAPK pathways were ...

The immune system is increasingly recognized for its role in the genesis and progression of hypertension. The adrenal gland is a major site that coordinates the stress response via the ...

Objectives We have previously described the antifibrotic role of the soluble guanylate cyclase (sGC). The mode of action ... sGC stimulation blocked the phosphorylation of ERK. In vivo, sGC ...