Levosimendan enhances the cAMP-PKA pathway by inhibiting PDE3, amplifying beneficial effects. Solid lines represent direct actions, while dashed lines indicate indirect or secondary effects. β1-AR, ...

In recognising this UK Sport’s approach to funding reflects that journey and works on the basis of an athlete pathway with three clear and distinct levels that make up the World Class Pathway. The two ...

More than three years after the Pathways Alliance oilsands group first announced plans for a proposed $16.5-billion carbon capture network in northern Alberta, the consortium still hasn’t given ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Farnesyl pyrophosphate derivatives bearing an additional oxygen atom at position 5 ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

Mainstreaming the below protection principles listed in no particular order of importance will allow to maximize the protection impact of complementary pathways. Complementary pathways help enhance ...

Job Offer stream No Job Offer stream You need to meet the work experience, education and language requirements. Through the EMPP, we’ll waive application and biometric fees for you and your dependants ...

Introduction: Guanylate cyclase C (GC-C) has been detected in the rodent brain in neurons of the cerebral cortex, amygdala, midbrain, hypothalamus, and cerebellum. Methods: In this study we determined ...

In ancient Rome, the 2-faced mythological Janus God symbolized the duality of the principles of presiding over all beginnings and transitions, whether abstract or concrete. 1 The bipolar concepts ...