New research suggests that δ-receptor agonists regulate intestinal motility and relieve abdominal pain in a mouse model of irritable bowel syndrome, potentially offering a novel CNS-targeted ...

One of the reasons for this dramatic, full-body response is that naloxone binds to opioid receptors all over the body, triggering involvement from organs like the skin and intestines, and not just ...

A118G (43AA, 19AG, 18GG) 80 Taiwan females following abdominal hysterectomy GG had significantly higher postoperative day 1 morphine requirements [104] A118G Caucasians: 66 = AA, 29AG; Africans: 1 ...

Neal’s upcoming research hopes to determine if CBD use would affect opioids like morphine in the body. Credit: Neuroscience News “This research will open a new avenue for anyone in the field of ...

Preliminary data from the team has already shown that in mouse models inhibiting the M5-receptor significantly reduces the addiction to prescribed opioids, whilst still maintaining pain relief ...

University of Mississippi researchers have discovered how a compound found in cannabis might be used to mitigate the negative effects of THC, a psychoactive compound in the plant. This ...

One of the next research frontiers involves investigating whether CBD interferes with opioids like morphine. If CBD negatively interacts with opioid receptors, it could reduce the efficacy of opioids, ...

Purpose. Published reports on placebo-controlled clinical trials and other studies investigating the use of pure opioid antagonists for the prevention and treatment of opioid-induced pruritus (OIP ...

"In the event that CBD binds to an opioid receptor, you could have negative interplay with opiate drugs like morphine," Neal said. "If you're getting pain relief from opiates, and if CBD ...