Amid these soaring cases, particularly in underserved and remote communities in the Prairies, the Multiplo® TP/HIV rapid self-test and non-professional tests provides a 'missing key' to help reach the ...
Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...
Adriel Chen and Devi Sridhar discuss the outbreak of Paediatric Inflammatory Multisystem Syndrome in 2020 and consider what lessons we can learn In mid-March 2020 and into April 2020, paediatric wards ...
Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...