Despite the high prevalence and morbidity of osteoarthritis (OA), an effective treatment for this disease is currently lacking. Restoration of the diseased articular cartilage in patients with OA ...

Cartilage lesions and osteoarthritis (OA) presents an ever-increasing clinical and socioeconomic burden. Synovial inflammation and articular inflammatory environment are the key factor for ...

zju.edu.cn Objectives This study investigated the stage-specific and location-specific deposition and characteristics of minerals in human osteoarthritis (OA) cartilages via multiple ... compositional ...

Objective To (1) develop and evaluate a machine learning model incorporating gait and physical activity to predict medial tibiofemoral cartilage worsening over 2 years in individuals without advanced ...

A computer model of the cellular environment inside the knee developed by UT Southwestern Medical Center researchers sheds ...

In animal models of arthritis, blockade of RANKL–RANK ... the inhibitory effect of RANKL blockade on proteoglycan loss from articular cartilage varies between the different models, whereas ...

Nov. 13, 2024 — A new study by medicine safety experts found the use of gabapentinoids -- medicines widely used to treat neuropathic pain -- increased the risk of hip fractures, especially in ...

The chronic pain of arthritis and the medications used to treat it can drain you. What can you do day to day to ease the fatigue?

Nov. 13, 2024 — The use of biologic and targeted therapies for children with juvenile idiopathic arthritis (JIA) surpassed more typical therapies in recent years, according to ...

The term osteoarthritis refers to a group of disorders that result in the primarily mechanically induced structural and functional failure of synovial joints. Here, the authors show that reduced ...

Data sources: Medline, Embase, Scientific Citation Index, CINAHL, Cochrane Library, and conference abstracts in the past 2 years from the British Society for Rheumatology, the European League Against ...

Rheumatoid arthritis (RA) is an inflammatory, autoimmune condition that affects not only joints but also organs, including eyes. While it can have painful and debilitating effects if left untreated, ...