Deep functional characterization of Fragile X syndrome patient and isogenic neurons using all-optical electrophysiology and machine learning identifies a validated, FMR1-dependent cellular ...
Glutamate uptake is mainly accomplished by astrocytes which either convert glutamate to glutamine or feed it into their own metabolism. Normally, the astrocytic glutamate transporters are indirectly ...
Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...
Monosodium glutamate (MSG) is a flavor enhancer that has been used for more than a century. At some point, however, it started to get a bad reputation and was said to be associated with various health ...
indicates that mutant huntingtin is also present in the nuclei of astrocytes, a phenomenon that becomes more robust with age and corresponds with a downregulation of glutamate transporters in ...
percent of somas active. (F), Percentage of domains active vs. percent of somas active. Mean ± SEM. Pearson correlation. (A), Astrocyte and ROIs. Scale bar = 10 µm. (B), Pseudocolor Ca 2+ images ...
This fundamental work provides evidence that glutamate and GABA are released from different synaptic vesicles at supramammillary axon terminals onto granule cells of the dentate gyrus. The study uses ...
We transduced mouse cortical astrocytes cultured from four litters of embryonic wildtype (WT ... GS protein expression was maintained while GFAP declined with cell passaging but was still detectable ...
Understanding the neurodegenerative processes involved in MS, particularly the role of white matter (WM) and grey matter (GM), may help clinicians to diagnose the disease earlier and maximize ...