indicates that mutant huntingtin is also present in the nuclei of astrocytes, a phenomenon that becomes more robust with age and corresponds with a downregulation of glutamate transporters in ...

Release of neurotransmitters such as glutamate from astrocytes can contribute to ischemic brain damage. Because astrocytes are coupled into networks by gap junctions, they are also important in ...

Astrocytes from both groups had deficits in glutamate signaling. The cool part is what happened next: When they exposed astrocytes to clozapine, glutamate signaling normalized—but only in the ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

Some examples of mouse models in which astrocyte protein function is altered are detailed in Table 1. In addition to cellular hypertrophy and upregulation of specific genes associated with ...