indicates that mutant huntingtin is also present in the nuclei of astrocytes, a phenomenon that becomes more robust with age and corresponds with a downregulation of glutamate transporters in ...

This review considers the role that optic nerve head astrocytes might play in the initiation of axon damage, based on the hypothesis that these cells are sensitive to mechanical or ischaemic ...

Release of neurotransmitters such as glutamate from astrocytes can contribute to ischemic brain damage. Because astrocytes are coupled into networks by gap junctions, they are also important in ...

Some examples of mouse models in which astrocyte protein function is altered are detailed in Table 1. In addition to cellular hypertrophy and upregulation of specific genes associated with ...

Astrocytes from both groups had deficits in glutamate signaling. The cool part is what happened next: When they exposed astrocytes to clozapine, glutamate signaling normalized—but only in the ...