High tumor levels were more likely to be present in the untreated and NK-92-treated mice than in mice treated with NK-92/5.28.z cell therapy. Due to the strong autofluorescence properties of analyzed ...

Here we could show that tumor cells of PC besides being senescent also exhibit stem cell features ... We would like to acknowledge the Lighthouse Core Facility, Freiburg for their assistance with ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

4 Institute of Pathology and Comprehensive Cancer Center EMN ... targeting chimeric antigen receptor (CAR) T-cell therapy can induce long-term drug-free remission in patients with autoimmune diseases ...

Design We harvested 42 samples from eight HCC patients and evaluated tumour heterogeneity using whole-exome sequencing, RNA sequencing, mass spectrometry-based proteomics and metabolomics, cytometry ...

The pre-B-cell receptor (pre-BCR), which comprises ... of cellular transformation and development of cancer. During their development, B cells generate diverse antigen receptor specificities ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Upper gastrointestinal endoscopy revealed an ulcer measuring 2 cm in diameter in the greater curvature, a biopsy from which confirmed a diagnosis of signet ring cell carcinoma. Thus, a final diagnosis ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

Feb. 3, 2025 — Researchers have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune ... Study Establishes Link ...