I-DXd targets B7-H3, a protein overexpressed on the surface of a wide variety of cancer cells that binds to the CD28 family of receptors, which includes PD-1, targeted by MSD's widely used ...
The Vδ1 TCR recognizes CD1d and its presented lipids, and its expression of NKp30 and NKp44 receptors can bind to ligands B7-H6. In addition to this ... Recent studies have indicated that ...
The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical ...
B7-H3, also known as CD276, is an immunoregulatory protein that is overexpressed in tumour tissue, notably in lung, breast, ovarian, gastric, and brain cancer, as well as squamous cell carcinoma ...
The three-signal paradigm tries to capture how the innate immune system instructs adaptive immune responses in three well-defined actions: (1) presentation of antigenic peptides in the context of MHC ...
We used a unique 3D microfluidic model of tumors to investigate the mechanisms of treatment resistance to CAR-T cells that were designed to target B7-H3, a common antigen in solid tumor cancers.
Correspondence to Dr Zhanju Liu, Department of Gastroenterology, The Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, China; liuzhanju88@126.com; and Dr Yingzi Cong, Department of ...
Biotin, also known as vitamin B7, is an essential vitamin that helps convert food into energy. The most efficient way to fill up on the micronutrient? Eating biotin-rich foods. You see ...