Together with researchers at Newcastle University, the researchers now demonstrate how the protein IGFBP7 affects the ability of the beta cells to secrete insulin. The protein IGFBP7, which is ...
Obesity can cause insulin resistance, which, in turn, causes the beta cells of the pancreas to secrete more insulin, leading to hyperinsulinemia and a number of associated diseases that can cause ...
This method not only preserves the islets' structural integrity but also maintains their ability to secrete insulin ... models of how insulin is released from pancreatic beta cells.
Beta Bionics is aiming to raise around $114.4 million to fund development of its iLet automated insulin delivery system, the company said in an updated securities filing last week. The update ...
Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.
The therapy takes the form of stem cell-derived human pancreatic islet cells, which secrete insulin in the body in ... a gene-editing therapy for beta thalassemia and sickle cell disease.