The U.S. Food and Drug Administration (FDA) has granted andecaliximab a Rare Pediatric Disease Designation (RPDD) for the treatment of FOP. An RPDD designation is granted to potential treatments for ...
Bone marrow stimulation techniques such as microfracture are primarily used to treat focal chondral defects; the evidence for the use of these techniques for knee OA remains unclear. The goal of ...
The paper presents a streamlined new approach for functional validation of genes known to underlie fragile bone disorders in a relatively high throughput, using CRISPR-mediated knockouts and a number ...