引言肿瘤免疫治疗已是癌症治疗的重要方向，尤其是免疫检查点抑制剂（如PD-1/PD-L1抑制剂）的成功应用，使得癌症治疗迎来了新的曙光。然而，即使这些治疗方法在部分患者中表现出显著疗效，仍有大量患者未能得到有效的治疗。这种现象背后，隐藏着肿瘤免疫逃逸和 ...

Mozart Therapeutics, the leading developer of CD8 Treg network modulators in autoimmune disease, announces the presentation ...

Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...

Researchers reveal that gut microbiota influence the effectiveness of immune checkpoint inhibitors (ICIs) in cancer treatment ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Improving the balance between proinflammatory T cells and anti-inflammatory regulatory T cells (Tregs) may be an attractive approach for treating atherosclerosis ... A cell suspension obtained by ...

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调节性T细胞是维持机体免疫稳态的CD4+ T细胞亚群，也是肿瘤微环境中免疫抑制屏障的主要构成细胞。因此，特异性地调控肿瘤微环境的Treg细胞使其功能与稳定性发生改变，将能够促进肿瘤杀伤反应的发生。

细菌性肺炎是一种严重的公共卫生负担，它不仅导致了大量的发病率和死亡率，还带来了沉重的医疗成本。尽管抗生素和辅助治疗是目前的主要治疗手段，但对于疾病发病机制的深入理解仍然有限。

The Financial Conduct Authority (FCA) says it will remove unnecessary regulations and relax some of the rules firms must adhere to in response to the UK government’s calls to remove barriers to ...

Comparatively, GZMB-expressing KIR+ CD8+ T-cells have been found to suppress autoimmunity by eliminating autoreactive CD4+ T-cells. The current study is the first to report the persistence and re ...