编辑丨王多鱼排版丨水成文抗 PD-1 联合仑伐替尼（lenvatinib，一种多靶点受体酪氨酸激酶抑制剂）治疗在多种肿瘤中均显示出临床疗效，但潜在的免疫学机制尚不清楚。2025 年 1 月 30 ...

*仅供医学专业人士阅读参考“过度劳累，难免会虚”，估计各位脑子里已经对上某经典产品的广告画面了吧？奇点糕可是一直觉得，抗癌的主力——CD8+细胞毒性T细胞（CTLs）也非常适合在这种广告里出镜，毕竟它们太容易在肿瘤微环境里耗竭或功能异常嘛。虽说免疫检 ...

Figure 3: Direct CD4 + T-cell allorecognition for provision of T-cell help for the generation of self-MHC restricted T-cell responses to tumor peptides. The optimal allogeneic dendritic cell for ...

Priya Hays, Hays Documentation Specialists, discusses innovations and advancements in the development of personalized cancer ...

We also determined which CD4 + T cell population is critical for induction of negative regulation of CTL tumor immunosurveillance, and found it was dependent on CD1-restricted NKT cells.

在Nature Cancer期刊以长文的形式发表了题为“ETV7 limits the antiviral and anti-tumor efficacy of CD8+ T cells by diverting their fate towards exhaustion （ETV7通过促进CD8+ T细胞命运向耗竭的转化，限制CD8+ T细胞抗病毒和抗肿瘤的功能）的研究论文 CD8 + ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Typically, in advancing disease, as the immune system becomes exhausted, it is less able to produce T-cells to defend itself. The CD4/CD8 percentage helps healthcare practitioners see this.

The stem-like CD4 T cells have the ability to renew themselves and transform into different immune cell types. These cells ...