ORLADEYO ® (berotralstat) is the first and only oral therapy designed specifically to prevent attacks of hereditary ...

Pfizer Inc. (NYSE: PFE) today announced positive topline results from the progression-free survival (PFS) analysis of the ...

Medications called CYP3A4 inhibitors block CYP3A4 from working ... Medications called CYP3A4 inducers stimulate the production of this enzyme. Higher levels of this enzyme can break down Ubrelvy ...

Objective To determine whether new users of proton pump inhibitors (PPIs) are at an increased risk of gastric cancer compared with new users of histamine-2 receptor antagonists (H2RAs). Design Using ...

Protein interactions play a crucial role in regulating cellular mechanisms, highlighting the need for effective methods to control these processes. In this regard, chemical inducers of proximity (CIPs ...

Avoid co-administration of XOLREMDI and strong CYP3A4 inducers. Reduce XOLREMDI daily dosage when administered with strong CYP3A4 inhibitors. Monitor more frequently for adverse reactions associated ...

By catalyzing the reduction of lipid peroxides, GPX4 protects cells from oxidative damage and is therefore considered an inhibitor of ferroptosis ... Therefore, research into the combination of ...

Aromatase is an enzyme that converts testosterone to estradiol, a type of estrogen. One study found that taking an estrogen blocker called an aromatase inhibitor while on testosterone therapy reduced ...

Using genetic markers to adjust initial doses of cyclosporine or tacrolimus may prove difficult, considering the variety of polymorphisms known to affect CYP3A4, CYP3A5, and MDR1. The current ...

The Inspiring Learning Group owned 11 Kingswood camps, with Kingswood having been the largest programme provider for the National Citizen Service. Kingswood, whose history dates to the 1980s and ...