This heterogeneity should be accounted for in obesity epidemic assessment, since different obesity forms may result in different clinical consequences, including cancer incidence and outcome.

Scientists say identification of two epigenetically different states in mouse model opens door to "entirely new world of ...

1Integrated Bioanalysis, Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca, Cambridge, United Kingdom.

For patients with localized prostate cancer (PCa), tissue-based genomic classifiers (GCs) do not consistently influence risk ...

The genetic and phenotypic heterogeneity among cancer cells and the interplay between them and the tumor microenvironment are two fundamental elements at play in cancer initiation, progression and ...

Tumour heterogeneity describes differences between tumours of the same type in different patients, and between cancer cells within a tumour. Both can lead to different responses to therapy.

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

Scientists discover hidden patterns that could predict disease decades in advance In a nutshell Early development matters: ...

D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

Tests do not consistently influence risk classification or treatment decisions; authors call for well-designed trials on role of GC tests in newly diagnosed PCa. (HealthDay News) — For patients ...