With the latest developments, Geninus’s single-cell sequencing technology is expanding its role to become a tool for diagnosing cancer. “We’re living in an era when anyone can analyse their ...

As single-cell sequencing approaches help to reveal the presence and features of non-tumour cells in many cancer types, spatial transcriptomics could shed further light on how their interactions ...

promoting cancer cell growth and drug resistance through paracrine activities, and inducing M2-type macrophage polarization (4). Some investigators have identified multiple non-immune mesenchymal cell ...

Materials and methods: In order to better understand malignant cervical cancer epithelial cells (EPCs), this study used bulk RNA-seq data from UCSC in conjunction with single-cell RNA sequencing data ...

During training, we employ tissue and technology-aware oversampling and domain-invariant training to enhance performance on underrepresented cancer types and sequencing technologies. We propose ...

What is Single-Cell Sequencing? Single-cell sequencing is a revolutionary technology that allows researchers to analyze the genetic material of individual cells, providing unprecedented insights into ...

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

This manuscript offers valuable insights by identifying two distinct liver cancer subtypes through multi-omics integration and developing a robust prognostic model, validated across various datasets, ...

These approaches are providing unparalleled insight into cancer-related questions around immunity, tumor plasticity and metastasis, regeneration, wound healing, and immunotherapy. Our mission is to ...

However, the response rate of ICB therapy remains low (below 20%), which is possibly due to heterogeneity of HCC cells and the tumor microenvironment (TME). Studies have shown that cancer-associated ...